Thrombus - 2008

The WRIGHT project: update
Patrick Kesteven
pp 1-3
Following the death of a young woman from massive pulmonary embolism after a flight in 2000, there has been intense media interest in traveller’s thrombosis. At that time it was generally accepted that such a condition existed but no one knew the extent of the problem or what should be done.

Comment: Thromboprophylaxis in pregnancy
Peter Rose
pp 2-2
The role of thromboprophylaxis in pregnancy for the prevention of venous thromboembolism (VTE) is still a problem for obstetricians and haematologists. Considerable variability remains in practice for VTE thromboprophylaxis in pregnancy, mainly due to the lack of prospective studies in this group of patients.

The design and implementation of protocols for venous thromboembolism
Paul Harrison
pp 4-5
Venous thromboembolism (VTE), comprising both deep vein thrombosis (DVT) and pulmonary embolism (PE), is a relatively common disease, with an incidence in Europe of approximately 100 per 100,000, for DVT, and 50 per 100,000 for PE. Risk factors for the development of VTE are well known and include: increasing age, immobility, surgery, malignancy, thrombophilia, pregnancy and heart failure. Given the aging population in the UK, the ongoing impact should not be underestimated.

NICE guidance on atrial fibrillation
David Fitzmaurice
pp 6-6
The atrial fibrillation (AF) guideline produced by the National Institute for Health and Clinical Excellence (NICE) demonstrates a huge commitment of time and effort by the guideline development group led by Professor Lip.1While the guideline is overtly evidence-based, there remains room for some debate over several issues. The guideline follows the standard NICE format, with background to the problem, a statement of the evidence, a section entitled ‘from evidence to recommendations’ and finally a set of recommendations with the appropriate evidence level stated.

Nursing symposium of the British Society for Haemostasis and Thrombosis
Ellen Murray and Caroline Baglin
pp 7-7
The British Society for Haemostasis and Thrombosis (BSHT) 2007 conference in Bath was a combined meeting with the UK Haemophilia Centre Doctors’ Organisation (UKHCDO). The meeting consisted of invitational lectures, a nursing symposium, posters, free communications, and a trade exhibition. This article is a report of the nursing symposium, a new feature of the conference, led and chaired by nurses working in the field of haemostasis and thrombosis.

Planning an international normalised ratio testing service
Phil Carson
pp 9-11
Increasing workloads and concerns regarding quality of care have resulted in a re-evaluation of practice and the consideration of alternative models of care for anticoagulant therapy. Satisfactory desktop coagulometers have allowed rapid testing of the international normalised ratio (INR) – the routine monitoring test of oral anticoagulant therapy – to become attractive to sites for one-stop clinics. While more expensive in terms of test cost, this can be outweighed by the timesaving advantages and an improved patient pathway.

Thrombus was previously supported by Bayer from 2014 to 2016, by Boehringer Ingelheim from 2009 to 2013, by sanofi-aventis from 2007 to 2008 and by Leo Pharma from 1998 to 2006.

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ISSN 1369-8117 (Print) ISSN 2045-7855 (Online)